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We calculated interpregnancy interval as the time between one


For consistency with previous studies,1 2 5 we modelled interpregnancy interval as a categorical variable, classed as: 0 5 months, 6 11 months, 12 17 months pandora jewellery, 18 23 months (as the reference category), 24 59 months, 60 119 months, and 120 months or longer. We calculated interpregnancy interval as the time between one birth and the estimated start of the pregnancy of the subsequent birth (birth date minus estimated gestational age). We also adjusted for possible confounders (see below).

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pandora charms Two members of the team are practising physicians (SV and JN), and two others are members of the CONSORT and EQUATOR (Enhanced Quality and Transparency of Reporting) Network executive (DGA and DM). The CENT Statement was developed in accordance with the process developed by members of EQUATOR executive group.22Pre meeting activitiesIn order to assess whether a reporting guideline for N of 1 trials was indeed warranted, members of the CENT group (CB, MS, LS, SV) undertook a systematic review to assess the design and reporting of N of 1 trials in the medical literature.5 This work confirmed the heterogeneity in N of 1 trials, and large inadequacies in their reporting, as described above.Between February 2009 and April 2009, a modified Delphi process was carried out to seek consensus on a set of potential reporting items (n=55) for N of 1 trials. This initial list was developed based on the characteristics of published trials guided by our systematic review and reporting elements from the CONSORT 2010 checklist.7 A two round survey was sent out to 56 international experts of N of 1 trialists, biostatisticians, clinical epidemiologists, reporting guideline developers, biomedical journal editors, and health research funders, of whom 75% and 62% responded in rounds 1 and 2, respectively. pandora charms

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